Efavirenz (EFV) is a well-known, effective anti-retroviral drug long used in first-line treatment for children and adults with HIV and HIV/AIDS. Due to its narrow window of effective concentrations, between 1 and 4 µg/mL, and neurological side effects at supratherapeutic levels, several investigations into the pharmacokinetics of the drug and its…

This study explores the cultural construction of "difficult" temperament in the first 2 years of life, as well as the logistical and thematic continuity across infancy and childhood in what mothers perceive as difficult. It extends earlier work regarding older children in six cultural sites: Italy, the Netherlands, Poland, Spain, Sweden,…

Urban and rural grandmothers (n = 20) in Botswana participated in focus groups to learn their expectations for the acquisition of skills by preschool children. Their expectations for self-care, traditional politeness, and participation in household chores were dramatically earlier than developmental timetables reported for Western middle-class…

Recent years have witnessed increasing attention to early childhood education and care as a foundation for children's successful development in school and beyond. The great majority of children in postindustrial societies now attend preschools or daycare, making this setting a major part of their culturally constructed developmental niches.…

The seven papers in this issue address a variety of challenges that parents in several different cultural places encounter as they do their best to ensure their children's safe, happy, and successful development from infancy through middle childhood: infant sleep, developmental agendas, temperament, preschools, academic success, and learning to be…

Research by Xinyin Chen and others has documented that in past decades, shyness in Chinese children was associated with leadership, peer-acceptance, and academic achievement. In contemporary China, shyness predicts maladaptive youth outcomes. Although social, political, and economic transitions are presumed to be responsible for this shift, little…

Ethnotheories of immigrant parents residing in the Netherlands are reshaped in response to the multiple and diverse educational practices they come in contact with after migration. Network analyses of "parenting relationships" of first generation Dutch-Moroccan parents living in the Netherlands show that they borrow from diverse…

Although children's school success is a parental goal in most cultures, there is wide cultural variation in the qualities that parents most wish their children to develop for that purpose. A questionnaire contained forty-one child qualities was administered to 757 parents in seven cultural communities in Australia, Italy, the Netherlands, Poland,…

One of the earliest challenges for infants and their parents is developing a diurnal sleep--wake cycle. Although the human biological rhythm is circadian by nature, its development varies across cultures, based in part on "zeitgebers" (German: literally "time-givers") or environmental cues. This study uses the developmental…

The current study investigated language development of children residing in institutional care (IC) in Russia, compared to peers raised by biological family care (BFC). We used standardized behavioral testing (Preschool Language Scale-5, McArthur CDI), and an event-related potential picture-word matching paradigm. Children in IC significantly…

The current study investigated the long-term effects of institutionalization on the inhibitory control of young adults raised in orphanages using the color-word Stroop task. We examined whether young adults raised in institutions (IC group; n = 24; M = 22.17 years, SD = 6.7) would demonstrate poorer behavioral performance and atypical neural…

Under conditions of suboptimal parental care, children with specific temperamental features have been shown to be especially vulnerable to the effects of stress. Most studies of temperamentally vulnerable children have been conducted using parental questionnaires, which are unfortunately not completely objective. An alternative approach, the use…

Health disparities in American Indian/Alaska Native (AI/AN) youth are well documented in the literature, as AI/AN youth appear to be more likely to experience trauma and engage in high-risk behavior, such as substance misuse and risky sexual behavior. These youth also appear disproportionally affected by the criminal justice system. Scholars…

There is an increasing attention to the phenomenon referred to as "twice exceptional" ("2e") children, namely, children who demonstrate both exceptional abilities and disabilities. In this essay, this concept is applied to delinquency and/or emotional-behavior disorder and gifts (talents) in the performance arts, exploring the…

A number of studies to this day have examined the role of maternal childhood trauma in parenting styles, mental health, and child attachment patterns; however, there are limited data on parenting of mothers who were raised in institutional care (IC) and involved in the child welfare system. The current review focuses on maternal history of…