This article introduces a classroom innovation, which was developed based on the principles of multiliteracies and scaffolding to enhance the mastery of multimodal skills of oral presentations among tertiary English as Second Language (ESL) students. The innovation, named the Responsive Multimodal Oral Presentation Pedagogy (RMO2P), was designed to systematically scaffold learning through the integration of TED (Technology, Education and Design) videos with Web 2.0, collaborative learning and teacher feedback. RMO2P aims to disrupt conventional ways of teaching by transforming the prevailing passiveness among ESL students during classroom learning into active engagement. This article explicates the rationale underpinning the responsive pedagogy and describes the five learning phases, which were developed based on the pedagogical principles and students' learning needs, and complemented the designated textbook. Classroom data revealed enhanced conceptual knowledge, engaged interests and improved oral presentation skills among the students after one semester of implementation. Hence, the findings affirm the potential of RMO2P as an innovation that can be adopted or adapted for the teaching of oral presentation skills in similar ESL contexts.