A dynamic partnership has been developed and cultivated between the North Carolina Central University (NCCU) and Durham Public Schools (DPS) called "The Learning Laboratory Initiative Partnership". The faculties involved in the partnership are from North Carolina Central University and Durham Public Schools Hillside New Tech High School. The overall purpose of the collaborative partnership between NCCU and Hillside New Tech High is to have a positive impact on 9-12 students' performance in science, mathematics, engineering, and technology (the STEM areas) by using current and emerging technologies, Instructional Design, the TPACK integration model, and a content faculty mentoring system. The partnership focuses on an intensive program of professional development and content mentoring of 9-12 teachers at Hillside New Tech. This project is divided into two phases based on the fiscal calendar. This research paper provides an overview of the project as a best practice model of technology integration and university-school partnership. It discusses the components of the project and provides a demonstration of professional development activities and teacher products as a result of the training provided by NCCU faculty for Hillside NT teachers.