Victimization based on actual or perceived sexual orientation or gender expression (SOGE) carries significant consequences. In this study, we examined how SOGE-based victimization and contextual factors predicted truancy among 886 Chilean students (M[subscript age] = 16.00, SD = 1.30) in four high schools. Victimization predicted truancy indirectly through its associations with students feeling unsafe at school--in general and specifically related to their SOGE. Furthermore, perceptions of a negative SOGE-based school climate predicted greater truancy, almost entirely indirectly through students feeling more unsafe at school in general and specifically related to their SOGE.