This article presents a case study that illustrates the paradigmatic shift in higher education from content-centered teaching to learning-centered academic programs. This pragmatic change, triggered by the STEM movement, calls for the introduction of success measures in the course development process. The course described in this paper illustrates such a goal-driven approach to the development of an entire multidisciplinary curriculum in mechanical engineering and mechatronics. The effectiveness of this new curriculum was confirmed by findings of a survey of graduates of the first six graduating classes who studied on the basis of this curriculum.