This article investigated the impact of using e-learning models' with the principles of constructivism to enhance the critical thinking skills of students in higher education institutions. The study examines the effectiveness of e-learning model in enhancing critical thinking of students at university level. This effectiveness is measured by a critical thinking test. The target population for this study is undergraduate information systems' students enrolled in Spring 2005 and Fall 2006 semesters at Kuwait University. (Contains 3 tables and 1 figure.)