The design of a web-based course is discussed based upon considerations of content, pedagogy, learning styles, and assessment. The learning styles are examined as primary considerations and indeed dictate needed elements in a web-based course. Assessment is also considered in the initial planning of such a course. These design elements are discussed with particular web elements given for each design element. Further illustration of the design procedure can be seen by going to a freshman chemistry course referenced at the end of this article. All considerations discussed in this article may be used both for a web-enhanced course and a course taught totally online. This discussion was presented at EdMedia00 in Montreal, Canada.