Introduction: The present study aims to identify different profiles in self-concept and resilience. In addition, statistically significant differences in self-concept domains among the profiles previously identified are analyzed. Method: The AF5 Self-Concept Questionnaire ("Cuestionario de Autoconcepto AF5") and the Resilience Scale were administered to 114 young people with different disabilities (physical, intellectual, visual, and auditory), aged between 18 and 35 years (M = 26.22; DT = 4.02). Results: Cluster analyses enabled us to identify three different resilience profiles. Results also revealed statistically significant differences in resilience among the participants according to type of disability. This was also observed in most self-concept domains among profiles. Discussion y Conclusion: Results suggest the need to deepen our knowledge of resilience and to design self-concept programs for people with disabilities.