Current e-learning forms are commonly based on improving the learning process through the enhancement of certain skills in students, such as collaborative, competitive or problem-based learning. However, it seems that there is still no e-learning "formula" that gathers the implementation of a number of more generic educational principles in a single e-learning system or platform. Therefore, this paper presents a web-based framework for the creation, development and implementation of heterogeneous learning environments called CADI. It offers a graphical user interface for students to interact with only the need for any generic WiFi compliant device. Its innovative design allows the instructor to select and combine the developed resources to create varied activities, providing content adapted to every single device. The usefulness of the system was tested by introducing a case study to a group of senior college students. The experience showed that the use of the system helped students to achieve better results in their evaluation. It also showed that the students had no problems interacting with it from the outset, promoting their active learning. Design, implementation and assessment results of the system are also presented and analyzed. (Contains 6 tables and 9 figures.)