Research demonstrates that student-centered teaching strategies (tutoring, small-group learning, mastery-based learning, and individualized instruction) can help students excel. Many schools have turned to blended learning--integrating online learning into brick-and-mortar schools--to help implement these strategies sustainably and effectively. This paper examines how eight pioneering district, charter, and private schools and school networks with notable student success adopted blended learning and new staffing arrangements to better enable personalized instruction. Blended learning gave teachers more real-time student learning data so that schools could frequently regroup students, quickly respond to struggling students, and help teachers improve by pinpointing instructional planning and professional development issues. At the same time, innovative staffing arrangements helped the schools personalize learning by providing more students with great teaching. Key elements of these innovative staffing models included: (1) New roles for educators, often as part of a career path allowing development and support; (2) Intensive collaboration on small teaching teams; (3) Cultures of intensive coaching; and (4) Paid fellowships and residencies that enabled schools to train their own teachers.