The foundations for the content, design, and preparation of early childhood intervention e-learning lessons, performance checklists, and practice guides are described. Methods and procedures described in the microlearning, professional development, early childhood intervention, expert performance, and product design literatures were used to develop an integrated framework for guiding product development. The framework includes six components based on research findings about the relationships between the integrated framework methods and procedures and how the confluence of research evidence informed the development of evidence-informed early childhood intervention products. The use of the framework is described and illustrated for two sets of e-learning lessons, performance checklists, and practice guides.