The virtual classroom and distance education have created new teaching pedagogy. This study was carried out to investigate Virtual Classroom Instruction on Academic Performance of Educational Technology Students in Distance Education, Enugu State. The population for this study was limited to the Students in National Open University, Enugu study Centre. Simple random sampling technique was used to select forty respondents from the educational technology students. A researcher developed questionnaire was used to gather the needed data. Collected data were analyzed using frequency counts and percentage. The findings from this paper suggested that the students' acknowledged that the availability and use of virtual classroom influenced their academic performance. Although the virtual classroom available was adequate, it was not often utilized for instruction. Thus, the researcher recommended that the virtual classroom should be utilized for maximum learning.