Michel De Certeau's scholars have rarely explored the pedagogical potential of the French thinker's thought. This paper aims at reconstructing the question of the teaching practice in De Certeau's works and, building on such reconstruction, it proposes a possible 'heterological' comprehension of teaching. Moving from an early writing dealing specifically with the teacher's identity, the paper shows how the famous dyad of strategies and tactics exposed in The practice of everyday life can be usefully applied to teaching and studying and helps further elaborate the question of teaching. From this analysis, the teacher will emerge as the owner of a strategic knowledge that, if he wants to teach, needs to be altered by the uncanny and tactical presence of the student. Teaching will finally be shown as the practice of alteration of knowledge operated by the other of such knowledge, namely, the student. In such alteration of knowledge lies the potential of a heterological comprehension of teaching.