The Information Technology in Science (ITS) Center for Teaching and Learning was a National Science Foundation funded program to provide high-quality professional development for 7-12th grade science teachers. The subgroup on which this paper focuses was immersed in an innovative approach to understanding chemistry of the environment. The group was comprised of 10 high school science teachers representative of science classes taught at all grade levels (9-12th). A team of four university professors led the group. The professors developed inquiry modules and communicated some of the intricacies of their research for adaptation to the participants' classrooms. This paper communicates the successful implementation and lessons learned by scientists during the course of an inquiry-based curriculum during summer 2005. The process and pace at which the material was covered, qualitative information about the attitudes of the participants towards the curriculum, and implications for professional development from the point of view of the science team leaders will be discussed. Analysis of time spent with participants revealed the progression and type of activities chosen for the professional development experience were effective. Results from informal participant interviews revealed they were most comfortable in incorporating inquiry into their classrooms after having been immersed in it themselves.