Under the leadership of the University of Cincinnati, a unique, systemic collaboration of educational, business, nonprofit, civic and philanthropic organizations from Cincinnati and Northern Kentucky is addressing the challenges facing urban children and youth. Called Strive, it seeks to create a seamless educational pipeline beginning at birth, through K-12, postsecondary education or training, and into career success. Strive is outcome-focused and targets partner intervention activities at key transitions from pre-natal care through early college.