This study investigated the relationship between perceived knowledge of research methods, research self-efficacy, interest in learning about research, and interest in performing research-related tasks in one's career. The study also investigated the effect of a research methods course with both didactic and experiential components on these variables. Participants were 33 undergraduates enrolled in a research methods for the social sciences course. At Time 1, perceived knowledge of research was related to all variables; at Time 2, it was related to research self-efficacy and learning interest only. Both perceived knowledge and research self-efficacy increased significantly over the semester; however, interest did not. Implications for teaching and outcome assessment are discussed.