Chemistry and innovations have long been coexisting in the classroom and are essential criteria for assessment. Chemistry entrepreneurship is the art of commercializing chemistry innovations and ideas to a wider audience, taking them beyond classroom and assessment. The innovative ideas when realized with social relevance show prospects for individuals/graduates to become job creators with the potential to reduce unemployment and to enhance the economy. Students of chemistry thus have an opportunity to convert the classroom-based innovations into income creating sustainable living while studying. This lays a foundation to build a career in chemistry entrepreneurship upon course completion, to become an "employer rather than an employee". In this study, we have discussed the scope of classroom innovations, the ideation-action gap, and various factors that influence students to choose and build a chemistry entrepreneurial venture. We conducted a survey to understand students' exposure and perspective on making chemistry relevant to the real world through chemistry entrepreneurship. Finally, we propose a pedagogy to introduce chemistry entrepreneurship and to provide a platform for students to build a career based on their innovation in chemistry.