The development of a knowledge economy requires a nation to foster a robust foundation in science, technology, engineering, and mathematics (STEM). The countries of the Arab world, including the oil-rich nations of the Gulf, have made great strides in this regard, though much remains to be done. This article examines the cultural barriers these nations face, such as a lack of educational access and post-graduation employment opportunities for women, as well as systematic obstacles, such as poor quality of STEM education. The article also examines international partnerships with foreign institutions as viable solutions for the Arab world, with the case of Weill Cornell Medicine-Qatar presented as a case study of a sustainable, mutually beneficial endeavor. Recommendations are made for the near future, including the removal of antiquated restrictions on women and the continued development of international collaborations at all educational levels.