In this study we investigated the relationships between nomophobia, psychological resilience, and mindfulness using a covariance-based structural equation modelling (SEM) analysis and examined the mediating role of psychological resilience in the relationship between mindfulness and nomophobia. The sample comprised 300 Turkish adolescents between the ages of 14-19 years. Results indicated that nomophobia has a significant and negative relationship with each of mindfulness and psychological resilience, whereas there was a significant and positive relationship between mindfulness and psychological resilience. Psychological resilience significantly mediated the relationship between mindfulness and nomophobia. These findings imply that enhancement of mindfulness-based interventions may help strengthen psychological resilience and thereby prevent nomophobia.