The value of active learning for increasing student comprehension and retention of science, technology, engineering, and mathematics (STEM) concepts within undergraduate courses has proven to be beneficial many times over; however, barriers still exist for both instructors and students. For example, instructors are often left to decide what type of active learning activities to incorporate and how to implement them yet receive little to no formal training about how to do this effectively. Additionally, student resistance to active learning persists, which adds to the pressure faced by some instructors. Compounding these issues is the absence of high-speed Internet in some regions, which makes accessing active learning activities, many of which are offered through online commercial programs, impractical if not impossible for some students. This problem was highlighted during the pandemic when courses transitioned to being partially or fully online. In this article, I describe a novel active learning method that encourages students to cognitively engage with physiology concepts by using digital images to build structures and processes using an approach that is more accessible to everyone, regardless of Internet capabilities. This approach also provides instructors an option for creating their own active learning activity that may be more suitable for their specific level of students or learning outcomes.