Technology has the potential to make a significant impact on education at all learning levels, but it will be only as powerful as the degree to which it is integrated effectively into the total instructional program. Educators responsible for effective instruction must assume leadership in achieving this goal. This paper describes the background, objectives, and activities of a program in the Division of Instruction at the Maryland State Department of Education (MSDE) that is designed to develop and enhance this leadership at both the state and the local level. Program objectives are to: (1) enhance the Division of Instruction staff's ability to provide leadership for Maryland local education agencies in improving curriculum, instruction, and learning through effective integration of appropriate technology and related software; (2) provide state-level leadership and technical assistance to the Maryland Education Project--a cooperative effort to improve mathematics and science instruction through the use of technology, involving the MSDE Potomac Edison Power Company, six local school systems, and five institutions of higher education--in meeting the same goals; and (3) provide instructional effectiveness leadership for the initiatives outlined in the MSDE Strategic Plan for Educational Technology. (Author/GL)