The effect of a mathematic flashcard application on a hand-held computing device was examined across three individual second grade students with learning and behavioral disabilities. All of the students improved their subtraction scores by an average of 17% as measured by the district-created, curriculum-based assessment. The results of this study suggest that practice on a mobile computing device with a mathematic flashcard application can improve subtraction skills in second grade students with disabilities. (Contains 1 table and 1 figure.)