This paper describes a study of students' perceptions of the impact of accessibility and interactivity on successful distance education in the Health Professions. The study utilized both quantitative and qualitative data to determine how students perceived issues of accessibility and interactivity affecting their success in distance courses. The research found that both accessibility and interactivity are crucial to students' success in and satisfaction with distance education courses. In fact, issues of accessibility and interactivity are interconnected to such an extent that they can work together to either support or detract from students' success. Students, instructors, staff, departments, and the university administration must work together as a team to create the most readily accessible and interactive distance education possible. (Contains 37 references.) (Author)