This paper investigated the awareness and use of Web 2.0 tools by students at BA ISAGO University, Botswana. Structured questionnaires were used to collect data from the targeted respondents. The results revealed that students are quite familiar with most Web 2.0 tools, such as Facebook, Twitter, media sharing tools, Google Drive, and instant messaging. Even though students are very familiar with and aware of the identified tools, the study found that most students hardly used them. Some of the reasons given by the students include inadequate numbers of computers available to be used by the students in the computer laboratories and limited access to Internet services as well as power failures. Based on these findings, the study recommended integrating a large part of using Web 2.0 tools in the curricula and improving the university infrastructures to facilitate higher uptake and improvement in student skills and the drive to use the tools.