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Raboh, Ghada – Journal of Chemical Education, 2018
A high performance liquid chromatography (HPLC) experiment for the upper level analytical chemistry laboratory is described. The students consider the effect of mobile-phase composition and pH on the retention times of ionizable compounds in order to determine the acid dissociation constant, K[subscript a], of a phenolic acid. Results are analyzed…
Descriptors: Science Instruction, College Science, Undergraduate Study, Inquiry