The implementation of e-learning as a strategy has risen exponentially over the last 20 years as more adults use this medium to enhance their skills and acquire knowledge. The utilization of technology offers significant advantages to both learners and organizations in terms of cost, time and rich learning content. E-learning has been widely adopted in the western world, and companies and organizations in developing countries are increasingly taking advantage of e-learning tools to support education and skill upgrade of their workforce as a mechanism to compete in an increasingly global economy. E-learning has taken root in several African countries with the explosion of communications tools, internet and mobile technology. This perspective on practice addresses three key issues of e-learning in Africa (a) the adoption of e-learning in developing African countries, (b) the available e-learning resources and practices, and (c) the implications of e-learning on workforce training and development.