Research indicates that up to 65% of children diagnosed with ADHD may continue to display general behavior problems, as well as specific symptoms of ADHD, later in life. In most of the studies, ADHD college students' self-esteem is strongly aligned with their social skills. The purpose of this study was to find directions that will assist ADHD students to succeed at college by identifying which factors affect their social skills and self-esteem, and, consequently, affect their academic achievement, their lives, and their careers. This study used a mixed method approach in which qualitative and quantitative research were combined. There were 88 participants, 44 ADHD students and 44 non-ADHD students from two two-year community colleges and a four-year private university. For quantitative research, the 44 ADHD students and the 44 non ADHD students, from these three institutions, completed three surveys; the Profile Information Form, the Social Interaction Anxiety Scale Survey Schedule and the Rosenberg Self-Esteem Scale questionnaires. The T-Test and MANOVA were utilized to measure the significance of the ADHD students' social skills and self-esteem compared to non-ADHD students. In qualitative study, eight themes to emerge from the interview data are as follows: 1) Diagnosis/Childhood Experiences, 2) ADHD Symptoms, 3) Self Esteem, 4) Family Support, 5) College accommodations, 6) Social Skills, 7) Medication, and 8) Goals and Professions. The result of the T-Test and the MANOVA test also illustrate that college students with ADHD have a lower level of self-esteem and poorer social skills when compared to the group of students without ADHD. These eight themes illustrate that ADHD symptoms affect participants' self-esteem and social skills and that between their social skills and self-esteem affect their social interactions and their academic achievement in college. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://www.proquest.com/en-US/products/dissertations/individuals.shtml.]