Recent developments of e-learning specifications such as Learning Object Metadata (LOM), Sharable Content Object Reference Model (SCORM), Learning Design and other pedagogy research in semantic e-learning have shown a trend of applying innovative computational techniques, especially Semantic Web technologies, to promote existing content-focused learning services to semantic-aware and personalised learning services. To facilitate this transforming process, this paper presents a novel context-aware semantic e-learning approach to integrate content provision, learning process and learner personality in an integrated semantic e-learning framework. As the basis of the computational framework, a scalable and extensible generic context model is proposed to structure the semantics of contextual relations and concepts in various contexts, such as learning content description, learning model, knowledge object representation and learner personality. Corresponding technical and pedagogical developments of this framework also consider compatibility issues with existing technologies (e.g., XML/Resource Description Framework) and specifications (e.g., IEEE LOM) in order to achieve the best interoperability.