In this paper we discuss how and why core ideas can serve as the framework upon which chemistry curricula and assessment items are developed. While there are a number of projects that have specified "big ideas" or "anchoring concepts", the ways that these ideas are subsequently developed may inadvertently lead to fragmentation of knowledge, rather than construction of a coherent, contextualized framework. We present four core ideas that emerged as a consequence of a transformation effort at our institution and discuss the relationships between core ideas and more recognizable topics in the context of a general chemistry course. We show how commonly taught topics can be supported and developed on the basis of the core ideas and discuss why this approach can lead to a more expert-like framework upon which students can build their future understanding.