This study is to examine the attitudes of students towards the case studies based on mobile messaging in a pharmacotherapy introduction class. Case studies were divided into 4 groups, with 30 pharmacy students each group. Each group was required to share pharmaceutical care plans on WeChat by posting messages. A post-activity survey was conducted: Over 70% of the students agreed that mobile messaging-based case studies (MMBC) helped developing skills and knowledge and stimulating additional research and readings. Over 60% of the students felt that MMBC helped understanding others' viewpoints and sharing their experience and knowledge. More than half of the students agreed that MMBC was more convenient than traditional and internet-based case study. Less than 30% of the students agreed that the interaction with other students was good. The findings reflect the MMBC studies' popularity with students. Recommendations to use MMBC studies include (a) balance the merits, such as expressing opinions clearly and concisely, allowing for collaborative learning, with the drawbacks: distraction and the low quality of interactions; (b) use small groups for case discussion; (c) design a collaborative schedule dividing the discussion into different sections.