Using vignettes, levels of HIV stigma among university students (n = 971) were examined to identify the likelihood of judging and blaming or avoiding personal and intimate contact with an HIV-positive individual. Reactions to the vignettes showed judgment and blame and intimate avoidance were higher when HIV was contracted through unprotected sex. Additionally, interpersonal avoidance and judgment and blame were higher when HIV was contracted through intravenous drug use. The results of this study can aid educators and health personnel in developing resources better suited to address and reduce HIV stigmatization. (Contains 4 tables and 1 footnote.)