Objective: This article highlights the importance of incorporating ethnocultural contexts in prevention research and programming. We provide a case example from our research in youth violence prevention in Hawai'i. Methods: Data were collected in multiethnic communities on O'ahu. Focus groups were conducted with high school-aged youths of Native Hawaiian, Filipino, and Samoan ancestry. Results: In analyzing narrative data regarding the broad theme of ethnoculture, a deeper issue became apparent during the focus group discussions--negative ethnocultural stereotypes and discrimination. Conclusion: Understanding ethnocultural issues is critical in decision making regarding prevention programming, particularly the need for deep-structure, culturally grounded interventions.