Differences in how one says the same thing in two distinct languages often give rise to challenges for second language learners, which when addressed, allow them to become more competent language users. The present study investigates the use of communicative language teaching (CLT) on compliment responses in Standard American English for English major students at a university in Northeast Thailand. Results from analysis of the data from the pretest, posttest and questionnaires indicate that not only do the CLT lessons designed with blended mechanical, meaningful, and communicative activities help students improve skills in responding to compliments in Standard American English, but these activities together with peer teaching also provide them with plenty of opportunities to practice other skills in English which they previously acquired. The discussion of these findings offers practical suggestions for optimal use of CLT in Thai EFL teaching contexts. [Note: Two of the authors' names (Supath Kookiatikul and Oranuch Puangsak) shown on the first page are spelled incorrectly. The author section on page 55 shows the correct spelling (Supath Kookiattikoon and Oranuch Puangsuk).]