How do students with special needs learn best based on brain research? There was a great deal of strictly scientific information about different types of brain damage and how that can affect learning. Given this, it was surprising that there was very little information on ways in which to assist students with learning disabilities utilizing the scientific information in this field. What was available, related to best teaching practices and was mirrored in the generalized and abundant literature in the field. Several themes emerged throughout the research. The overarching theme was the role of stress and emotions and their effects on students with learning disabilities. Following closely behind this was the relationship of learning to prior knowledge. The last dealt with the issue of poor readers. A list of resources is presented.