This report of a National Conference on Regionalism and Regionalization in American Postsecondary Education contains an overview and summary of the final project report, a keynote address, four papers on the implications of regionalism, some reactor comments, an essay on leadership, and four descriptive accounts of operational regionalization activities. The contents of the report are as follows: "Regionalism in American Postsecondary Education: Concepts and Practices (Overview, Summary and Conclusions from the National Study)," by S. V. Martorana and Lawrence A. Nespoli; "Coming Conditions in Academe: A Backdrop to Regionalism in American Postsecondary Education," by Fred M. Hechinger; "Implications of Regionalism for State-Level Governmental Policies and Possible Legislative Concerns and Actions," by Ronald B. Stafford; "Some Observations on the Budgetary Implication of Regional Actions in Maryland," by H. Louis Stettler, III; "Implications of Regionalism for State-Level Planning and Coordination Efforts for Postsecondary Education," by Richard C. Hawk; "Implications of Regionalism for Postsecondary Institutions and State-Governed Systems," by Robert L. Gale; "The Importance of Leadership for Regionalism: Some Suggestions for Action," by Louis Rabineau; "Current and Future Status of Consortia," by Lewis D. Patterson; "Regionalism and Educational Brokering Services for Adults," by Francis U. Macy; "Postsecondary Education Planning Commissions: A Federal Role," by James F. Rogers; and "Expanding Regional Cooperation in Graduate and Professional Education," by Richard W. Jonsen.