Purpose: The paper offers commissioners and practitioners insights into how a gender and culturally sensitive COVID-19 vaccination clinic was set up in a local area that was experiencing lower uptake rates. Design/methodology/approach: This paper seeks to examine and share a city-wide approach to improve vaccine uptake in a large metropolitan city in the UK. Findings: In mitigating inequalities and ensuring underserved populations have access to the COVID-19 vaccine, there is a need to work with communities to develop vaccine clinics that provide a local, convenient and trusted offer that meets the needs of residents. Originality/value: Developing a local COVID vaccine offer that meets cultural needs focusing on an area of low uptake in a large metropolitan city.