This study served to investigate how information literacy instruction can alleviate information anxiety in online learners. While there has been much research to demonstrate that hands-on or activity-based learning is beneficial in reducing library anxiety, those studies have not been conducted for the online classroom. Using a required, first-semester course in the University of Southern California's School of Social Work online program, this study hypothesized that activity-based online library instruction sessions will result in a measurable reduction of information anxiety. Using a pre- and post-session survey instrument, this study discovered that activity-based instruction for online students may not be as effective in reducing information anxiety as previous research suggested.