This exploratory study examined the relationships among strengths use, spirituality, religion, and positive mental health of 109 traditional undergraduate, college-attending emerging adults in a public university in the southern region of the United States, often referred to as the Bible-Belt. Constructs of the study were guided by a student program for strengths development and engagement, the idea that spirituality is fundamental to students' lives while commitment to a specific religion decreases (Astin, Astin, & Lindholm, 2011), and prior research indicating strengths use contributed to well-being (Govindji & Linley, 2007; Proctor, Maltby, & Linley, 2009). Participants completed the Strengths Use Scale (SUS; Govindji & Linley, 2007), the Daily Spiritual Experience Scale (DSES; Underwood, 2006), the Santa Clara Strength of Religious Faith Questionnaire (SCSORF; Plante & Boccaccini, 1997a) and the Mental Health Continuum-Short Form (MHC-SF; Keyes, 2002, 2009). Seven research questions were generated from study variables and data were analyzed using Pearson's product-moment correlations and multiple regressions. Positive correlations were found among strengths use, spirituality, and positive mental health. Multiple regression analyses showed that strengths use contributed to 18.1% of the variance of positive mental health. Positive mental health could be predicted solely from strengths use; and strengths use, in turn, could be predicted solely from spirituality. Therefore, findings suggest that strengths use is possibly an intermediary variable between spirituality and positive mental health. Implications for the fields of counseling, counselor education, and higher education are discussed along with limitations and suggestions for future research. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://www.proquest.com/en-US/products/dissertations/individuals.shtml.]