This longitudinal study examined how academic self-efficacy, intrinsic motivation, and participation in an after-school program contributed to the academic achievement of Latino middle school students over the course of one school year. Participants were 47 Latino students in sixth through eighth grades who attended two public middle schools in which an after-school program was held that was specifically for Latino students. Results from ordinary least squares regression revealed that intrinsic motivation was positively associated with students GPAs, self-efficacy was a positive predictor of students' school attendance and standardized math achievement scores, and attendance at the after-school program also contributed positively to students' math achievement. Results from multilevel growth modeling showed that students' self-efficacy and intrinsic motivation remained stable across the school year and were not related to students' degree of participation in the after-school program. Several avenues for future research within the Latino student population are discussed. (Contains 1 table and 1 note.)