This study aims to create a comprehensive bibliometric map of published scientific articles on e-learning in mathematics education (ME). We used Web of Science (WoS) database to analyzed 341 articles published by 1018 authors representing 79 countries between 2012 and 2022. In this context, we examined scientific articles in terms of scientific production, network analysis, trend topics, thematic change, and conceptual structure. Bibliometric analysis was performed in the study. According to findings, the number of published articles differ according to the years, but the number of citations is constantly increasing. Albano, and Dello Iacono are the most prolific authors. The most productive institutions are Salerno and Black Sea Technical Universities. China, USA, and Russia lead the countries of the corresponding authors. According to the network analysis, the journals of Computers & Education and Computers in Human Behavior form strong links. The most used keywords are students, technology, and mathematics. The pandemic, COVID, reality, and process are trend topic titles. It determined that the best size reduction obtained in the conceptual analysis constituted approximately 31% of the total variability. We presented some suggestions based on the findings obtained at the end of the research.