In the study reported on here we sought to identify teaching and general stressors, and how they contributed to work-family conflict among female teachers in urban public schools in Kenya. A total of 375 female teachers with at least their youngest child not yet in primary school completed a survey of closed and open-ended questions. Role theory, stressors, and work-family conflict literature informed the study. The data were analysed using hierarchical regression and content analysis. Findings yielded some contradictory results suggesting that, while the work-family conflict is a universal construct, culture and socioeconomic factors likely influence the nature and the impact of stressors. That is, these teachers identified stressors not mentioned in previous Western literature and not captured by quantitative measures. For instance, the greatest stressor cited was domestic workers not being reliable. The study also indicated that disruptions in the normal flow of work was regarded as a stressor. In addition, a sick child, rather than its age, was regarded as a stressor. Theoretical and practical contributions of the study are provided.