Congenital heart disease is one of the most common pediatric chronic illnesses that can have an impact on the lives of affected children and their families. Despite the growing number of school-age children who live with congenital heart disease, few researchers have investigated the lives and well-being of these children and their families. The present study examined the school experiences, quality of life, and recommendations of children and families who live with congenital heart disease. Semi-structured interviews were conducted with 76 participants including school-age children who have congenital heart disease and their parent(s) or guardian(s). Results indicate that to optimize the school experiences of children and families who live with congenital heart disease, medical and school professionals who work with and support these individuals must consider what we term the "Five C's:" communication, confidentiality, consistency, competence, and compassion. (Contains 6 tables and 1 figure.)