The Regents of the University of Colorado engaged the National Center for Higher Education Management Systems (NCHEMS) to conduct a review of the reporting relationships and decision-making authority of the Board of Regents, the President of the System, the System Administrative Officers, and the Chancellors and senior officers of the four campuses, and to recommend guiding organizational principles for the University's future. This report documents the results of that review. The review drew upon lessons from the experience of other comparable university systems, while respecting University of Colorado's unique history, culture, and structure.