Publication Date
In 2024 | 0 |
Since 2023 | 0 |
Since 2020 (last 5 years) | 16 |
Since 2015 (last 10 years) | 16 |
Since 2005 (last 20 years) | 16 |
Descriptor
Neurological Impairments | 16 |
Animals | 10 |
Memory | 10 |
Brain Hemisphere Functions | 9 |
Cognitive Processes | 6 |
Spatial Ability | 5 |
Conditioning | 3 |
Genetics | 3 |
Symptoms (Individual… | 3 |
Therapy | 3 |
Alzheimers Disease | 2 |
More ▼ |
Source
Learning & Memory | 16 |
Author
Publication Type
Journal Articles | 16 |
Reports - Research | 13 |
Reports - Evaluative | 3 |
Education Level
Audience
Location
Laws, Policies, & Programs
Assessments and Surveys
What Works Clearinghouse Rating
Oberländer, Kristin; Witte, Victoria; Mallien, Anne Stephanie; Gass, Peter; Bengtson, C. Peter; Bading, Hilmar – Learning & Memory, 2022
Differences in the learning associated transcriptional profiles between mouse strains with distinct learning abilities could provide insight into the molecular basis of learning and memory. The inbred mouse strain DBA/2 shows deficits in hippocampus-dependent memory, yet the transcriptional responses to learning and the underlying mechanisms of…
Descriptors: Learning, Memory, Animals, Research
Jordan, Jake T.; Tong, Yi; Pytte, Carolyn L. – Learning & Memory, 2022
Plasticity is a neural phenomenon in which experience induces long-lasting changes to neuronal circuits and is at the center of most neurobiological theories of learning and memory. However, too much plasticity is maladaptive and must be balanced with substrate stability. Area CA3 of the hippocampus provides such a balance via hemispheric…
Descriptors: Spatial Ability, Brain Hemisphere Functions, Memory, Learning Processes
Gonzalez, Maria Carolina; Radiske, Andressa; Conde-Ocazionez, Sergio; Rossato, Janine I.; Bevilaqua, Lia R. M.; Cammarota, Martín – Learning & Memory, 2022
Hippocampal dopamine D1/D5 receptor-dependent destabilization is necessary for object recognition memory (ORM) updating through reconsolidation. Dopamine also regulates hippocampal theta and gamma oscillations, which are involved in novelty and memory processing. We found that, in adult male rats, ORM recall in the presence of a novel object, but…
Descriptors: Recall (Psychology), Brain Hemisphere Functions, Biochemistry, Neurological Impairments
Cawley-Bennett, Andrew T. J.; Frascino, Jennifer C.; Asp, Isabel E.; Golshan, Shahrokh; Bondi, Mark W.; Luo, Zhishang; Smith, Christine N. – Learning & Memory, 2022
Novel tests of semantic memory (SM)--for example, memory for news events (NE; news facts) or famous personalities--are useful for estimating the severity of retrograde amnesia. Individuals with mild cognitive impairment exhibit relatively intact SM/language on traditional neuropsychological tests but exhibit consistent impairment on novel tests of…
Descriptors: News Reporting, Current Events, Memory, Neurological Impairments
Fujiwara, Esther; Madan, Christopher R.; Caplan, Jeremy B.; Sommer, Tobias – Learning & Memory, 2021
The brain processes underlying impairing effects of emotional arousal on associative memory were previously attributed to two dissociable routes using high-resolution fMRI of the MTL (Madan et al. 2017). Extrahippocampal MTL regions supporting associative encoding of neutral pairs suggested unitization; conversely, associative encoding of negative…
Descriptors: Emotional Response, Arousal Patterns, Neurological Impairments, Paired Associate Learning
Shepherd, Elizabeth H.; Fournier, Neil M.; Sutherland, Robert J.; Lehmann, Hugo – Learning & Memory, 2021
Damage to the hippocampus (HPC) typically causes retrograde amnesia for contextual fear conditioning. Repeating the conditioning over several sessions, however, can eliminate the retrograde amnesic effects. This form of reinstatement thus permits modifications to networks that can support context memory retrieval in the absence of the HPC. The…
Descriptors: Brain Hemisphere Functions, Neurological Impairments, Fear, Memory
Anderson, Michael D.; Paylor, John W.; Scott, Gavin A.; Greba, Quentin; Winship, Ian R.; Howland, John G. – Learning & Memory, 2020
Perineuronal nets (PNNs) are specialized extracellular matrix structures that surround subsets of neurons throughout the central nervous system (CNS). They are made up of chondroitin sulfate proteoglycans (CSPGs), hyaluronan, tenascin-R, and many other link proteins that together make up their rigid and lattice-like structure. Modulation of PNNs…
Descriptors: Animals, Brain Hemisphere Functions, Novelty (Stimulus Dimension), Neurological Impairments
Schultz, Maria N.; Crawley, Jacqueline N. – Learning & Memory, 2020
Angelman syndrome is a rare neurodevelopmental disorder caused by a mutation in the maternal allele of the gene "Ube3a." The primary symptoms of Angelman syndrome are severe cognitive deficits, impaired motor functions, and speech disabilities. Analogous phenotypes have been detected in young adult "Ube3a" mice. Here, we…
Descriptors: Neurological Impairments, Genetics, Genetic Disorders, Symptoms (Individual Disorders)
Ammassari-Teule, Martine – Learning & Memory, 2020
Largely inspired from clinical concepts like brain reserve, cognitive reserve, and neural compensation, here we review data showing how neural circuits reorganize in presymptomatic and early symptomatic hAPP mice to maintain memory intact. By informing on molecular alterations and compensatory adaptations which take place in the brain before mice…
Descriptors: Brain, Cognitive Processes, Neurological Organization, Animals
Binder, Matthew S.; Kim, Andrew D.; Lugo, Joaquin N. – Learning & Memory, 2020
Memory deficits significantly decrease an individual's quality of life and are a pervasive comorbidity of epilepsy. Despite the various distinct processes of memory, the majority of epilepsy research has focused on seizures during the encoding phase of memory, therefore the effects of a seizure on other memory processes is relatively unknown. In…
Descriptors: Seizures, Memory, Neurological Impairments, Epilepsy
Rogers, Jack T.; Cahill, Catherine M. – Learning & Memory, 2020
A set of common-acting iron-responsive 5'untranslated region (5'UTR) motifs can fold into RNA stem loops that appear significant to the biology of cognitive declines of Parkinson's disease dementia (PDD), Lewy body dementia (LDD), and Alzheimer's disease (AD). Neurodegenerative diseases exhibit perturbations of iron homeostasis in defined brain…
Descriptors: Neurological Impairments, Dementia, Brain, Cognitive Processes
ApoE Isoform-Specific Differences in Behavior and Cognition Associated with Subchronic MPTP Exposure
Torres, Eileen Ruth S.; Boutros, Sydney Weber; Meshul, Charles K.; Raber, Jacob – Learning & Memory, 2020
Parkinson's disease (PD) is characterized clinically by progressive motor dysfunction; overt parkinsonism is often preceded by prodromal symptoms including disturbances in the sleep-wake cycle. Up to 80% of patients with PD also develop dementia. In humans, there are three major apolipoprotein E isoforms: E2, E3, and E4. Increased rate of dementia…
Descriptors: Neurological Impairments, Dementia, Genetics, Animals
Hippocampal Efferents to Retrosplenial Cortex and Lateral Septum Are Required for Memory Acquisition
Opalka, Ashley N.; Wang, Dong V. – Learning & Memory, 2020
Learning and memory involves a large neural network of many brain regions, including the notable hippocampus along with the retrosplenial cortex (RSC) and lateral septum (LS). Previous studies have established that the dorsal hippocampus (dHPC) plays a critical role during the acquisition and retrieval/expression of episodic memories. However, the…
Descriptors: Learning Processes, Memory, Brain Hemisphere Functions, Fear
Barker, Gareth Robert; Wong, Liang Fong; Uney, James B.; Warburton, Elizabeth C. – Learning & Memory, 2020
The medial prefrontal cortex (mPFC) is known to be critical for specific forms of long-term recognition memory, however the cellular mechanisms in the mPFC that underpin memory maintenance have not been well characterized. This study examined the importance of phosphorylation of cAMP responsive element binding protein (CREB) in the mPFC for…
Descriptors: Brain Hemisphere Functions, Long Term Memory, Recognition (Psychology), Spatial Ability
Nauer, Rachel K.; Schon, Karin; Stern, Chantal E. – Learning & Memory, 2020
With a rising aging population, it is important to develop behavioral tasks that assess and track cognitive decline, and to identify protective factors that promote healthy brain aging. Mnemonic discrimination tasks that rely on pattern separation mechanisms are a promising metric to detect subtle age-related memory impairments. Behavioral…
Descriptors: Mnemonics, Physical Fitness, Cognitive Ability, Aging (Individuals)
Previous Page | Next Page »
Pages: 1 | 2