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Direct linkBergstrom, Hadley C.; Lieberman, Abby G.; Graybeal, Carolyn; Lipkin, Anna M.; Holmes, Andrew – Learning & Memory, 2020
Most experimental preparations demonstrate a role for dorsolateral striatum (DLS) in stimulus-response, but not outcome-based, learning. Here, we assessed DLS involvement in a touchscreen-based reversal task requiring mice to update choice following a change in stimulus-reward contingencies. In vivo single-unit recordings in the DLS showed…
Descriptors: Brain Hemisphere Functions, Stimuli, Responses, Learning Processes
Bjorni, Max; Rovero, Natalie G.; Yang, Elissa R.; Holmes, Andrew; Halladay, Lindsay R. – Learning & Memory, 2020
While results from many past studies have implicated the bed nucleus of the stria terminalis (BNST) in mediating the expression of sustained negative affect, recent studies have highlighted a more complex role for BNST that includes aspects of fear learning in addition to defensive responding. As BNST is thought to encode ambiguous or…
Descriptors: Fear, Cues, Brain Hemisphere Functions, Learning Processes
