Research management is an emerging field of study and its development is significant to the advancement of research enterprise. Developing the science of research management requires investigating social mechanisms involved in research management. Yet, studies on social mechanisms of research management is lacking in the literature. To address this gap, this paper proposes importing methodologies and theories from other social science disciplines to study the social mechanisms of research management and to build the science of research management. The paper first articulates what constitutes the science of research management, then proposes to appropriate Design-Based Research (DBR), a methodology in education research, for building the science of research management while at the same time strengthening the theory-practice nexus. A study of education research is then presented to illustrate how DBR is used to enact the theory of homophily which is imported from sociology. It reveals an opportunity to use social designs to develop social relationships among teachers from different schools for networked learning. Such a research endeavour also has potential to advance theories of relationship-building in sociology. Inferring from the example as an analogue to what is suggested for research management, the paper advocates a way to reciprocally connect research management as an emerging research field with more established social science disciplines at large and to advance both the theory and practice of research management.