The purpose of this study was to illustrate the collaborative development of a teacher training program for teachers who have a child with cancer in their classroom. Five hundred twenty-eight kindergarten through 12th grade public school teachers were surveyed to identify their training needs. Based on these needs a computer-based training program was developed in collaboration with a review panel including 2 physicians and 1 child life specialist. Following construction of the program, 28 participants were recruited to pilot test the self-paced training program. Teachers' perceived knowledge and perceived preparedness increased significantly after completion of the training program as did their objective knowledge of childhood cancer. Overall, participants rated the training program as effective and easy to use. The majority of participants indicated an interest in using computer-based training programs in the future to meet their continuing education needs. The results of this study suggest that school practitioners can work collaboratively with medical practitioners to develop training programs for teachers of children with cancer. (Contains 3 tables.)