This study offers insights regarding the use of mobile devices by students to help educators in Library and Information Science (LIS) and across disciplines better understand their current and potential use. Using a web survey and descriptive content analysis methods, this article reports student perceptions of the role mobile devices play in LIS coursework, identifying areas where the technology is effective, providing recommendations regarding creative enhancements to course delivery, and offering insights for instructors into mobile-friendly course design and pedagogy. The data in this study indicate that current LIS students take their courses "on the go," moving easily between a formal learning setting to an informal one, and provide instructors with considerations for the multiple ways in which students may access course content and engage with others in their classes using mobile devices.