Peer relations researchers have suggested that dyadic and peer group relationship characteristics may interact with each other to affect behavior. Building on prior work that has pitted the relative effects of dyadic and peer group relationship characteristics on susceptibility to peer influence, the present study sought to integrate dyadic and group characteristics into a moderational model by testing whether friendship quality and peer group identification together exacerbate risk for conforming to peer norms for substance use. This longitudinal study included 387 early adolescents assessed annually for 4 years. Participants completed measures of perceived peer delinquency, friendship quality, peer group identification, and substance use frequency. Results indicated that perceived peer delinquency had the strongest association with substance use for adolescents characterized by high friendship quality and high peer group identification. These findings highlight the importance of considering the joint effects of multiple peer relationship characteristics on susceptibility to peer influence.