The current study examined the relationships between a personality metatrait (Stability consisting of conscientiousness, agreeableness, and neuroticism), self-esteem, and stress in an adult population of individuals with substance use disorders living in recovery homes. Adults (N = 229) residing in 42 residential recovery settings were interviewed as part of the first wave of a longitudinal study in three sites. Standard error of the mean analysis found significant effects for several demographic variables on Stability, and Stability was significantly related both directly and indirectly to stress. These findings suggest that individual differences at entry may influence recovery home effects and may be important to developing more effective aftercare systems.